Vaccinating women against pertussis during pregnancy is safe for both mothers and babies, the results of a recent study indicate. The study, published in the May 7, 2014, issue of the Journal of the American Medical Association, also found that immunization during pregnancy with the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine resulted in significantly higher concentrations of antibodies to all vaccine antigens in infants during their first 2 months of life.
The study began before the 2012 recommendation from the Advisory Committee on Immunization Practices that all women should receive the Tdap vaccine during every pregnancy and evaluated the safety and immunogenicity of administering the Tdap vaccine to expectant mothers during their third trimester. From October 2008 through May 2012, women at 30 to 32 weeks’ gestation were randomized to receive the Tdap vaccine or placebo.
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