All Evolocumab Device Options Available At Reduced List Price – Drug for nerve pain boosts high for opioid abusers. (866) 348-2889
All evolocumab (Repatha, Amgen) device options, including the Pre-Filled Syringe and Pushtronex® are now available at a lower list price of $5,850. The lower priced Repatha options are identical to the Repatha options currently available, but have been introduced to reduce out-of-pocket costs for patients, especially Medicare patients, according to a statement from Amgen officials.
Evolocumab is a human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). Repatha binds to PCSK9 and inhibits circulating PCSK9 from binding to the low-density lipoprotein (LDL) receptor (LDLR), preventing PCSK9-mediated LDLR degradation and permitting LDLR to recycle back to the liver cell surface. By inhibiting the binding of PCSK9 to LDLR, the increases the number of LDLRs available to clear LDL from the blood, thereby lowering LDL-C levels.