Broadly Neutralizing Antibodies Combination May Suppress HIV Without Antiretroviral Therapy – Drug for nerve pain boosts high for opioid abusers.

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Broadly Neutralizing Antibodies Combination May Suppress HIV Without Antiretroviral Therapy – Drug for nerve pain boosts high for opioid abusers. (866) 348-2889

A pair of new papers is fueling hope that a combination of next generation broadly neutralizing antibodies might be able to achieve long-term viral suppression of HIV without the need for a daily antiretroviral pill.

Both articles came out of a collaboration between German scientists and researchers at Rockefeller University in New York. Though the research is based on a small pool of participants, it suggests combining anti-HIV antibodies could help defeat resistance and suppress the virus.

With antiretroviral drugs, researchers have previously found that administering a single therapy is usually ineffective, since the virus quickly develops resistance to the drug. Thus, antiretroviral therapy (ART) is typically administered in multi-drug combinations.

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New Tele-Pharmacy Software Offers Face to Face Interaction Between Pharmacists and Patients – APhA submits compounding comments to FDA.

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New Tele-Pharmacy Software Offers Face to Face Interaction Between Pharmacists and Patients – APhA submits compounding comments to FDA. – (866) 348-2889.

Pharmacists are already one of the most accessible health care providers, and new developments in digital technology are making them easier than ever for patients to access.

Progressive Care is expanding more patient access to pharmacy care with their new proprietary tele-pharmacy software, Tele-PharmCo. The HIPPA-secured platform will allow patients to interact with pharmacists in real time through 2-way video consultations, according to a press release.

While the progression of pharmacy services toward automated technology and delivery services brings convenience, it eliminates the face to face conversation between providers and patients, Progressive Care CEO, Mars Shital, told Pharmacy Times.

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Eating to Preserve Brain Health and Prevent Disease: What Foods Should You Include? – Drug for nerve pain boosts high for opioid abusers.

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Eating to Preserve Brain Health and Prevent Disease: What Foods Should You Include? – Drug for nerve pain boosts high for opioid abusers. (866) 348-2889

While there is no single food known to boost brain health with aging, nutritionists recommend a balanced diet full of fruits, vegetables, legumes, whole grains, plant-based protein, and fish, as optimal for staying healthy and keeping the brain sharp. These foods often contain omega-3 fatty acids, Vitamin B, and antioxidants, which are known to improve brain health and function, according to a report published by Harvard Health Publishing.1

Lisa Mosconi, PhD, IHNC, a neuroscientist who specializes in Alzheimer’s disease prevention and nutrition coaching, agrees that diet is important in maintaining brain health with aging.2

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Positive Topline Results Shown for Dupilumab in Phase 3 Trials in Patients with CRSwNP – APhA submits compounding comments to FDA.

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Positive Topline Results Shown for Dupilumab in Phase 3 Trials in Patients with CRSwNP – APhA submits compounding comments to FDA. – (866) 348-2889.

All primary and secondary endpoints were met in a pair of pivotal Phase 3 placebo-controlled trials that evaluated Sanofi and Regeneron’s dupilumab product (Dupixent®) for adults with inadequately-controlled chronic rhinosinusitis with nasal polyps (CRSwNP).1

On the coprimary endpoints for both trials at 24 weeks, patients treated with dupilumab added to a standard-of-care corticosteroid nasal spray experienced a 51% and 57% improvement in their nasal congestion/obstruction severity compared to 15% and 19% improvement with nasal spray alone (placebo) (-1.25 and -1.34 for dupilumab compared to -0.38 and -0.45 for placebo, on a 0-3 scale ). Dupilumab treated patients had a 27% and 33% reduction in their nasal polyps score compared to a 4% and 7% increase for placebo (-1.71 and -1.89 for dupilumab compared to 0.10 and 0.17 for placebo, on a 0-8 scale that measures bilateral polyps size by endoscopy).1

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Treatment for HER2-Negative Breast Cancer with Germline BRCA Mutation Granted FDA Approval – Drug for nerve pain boosts high for opioid abusers.

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Treatment for HER2-Negative Breast Cancer with Germline BRCA Mutation Granted FDA Approval – Drug for nerve pain boosts high for opioid abusers. (866) 348-2889

Officials with the FDA have approved talazoparib (Talzenna, Pfizer) for the treatment of HER2-negative locally advanced or metastatic breast cancer with germline BRCA (gBRCA) mutations, according to a press release.

Talazoparib, a poly ADP-ribose polymerase (PARP) inhibitor, is indicated for patients with known deleterious or suspected deleterious gBRCA-mutated breast cancer who are selected for the therapy based on an FDA-approved companion diagnostic.

As a dual-mechanism PARP inhibitor, talazoparib both inhibits and traps the PARP enzyme, which may lead to heightened cell death, according to Pfizer.

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Increasing E-Cigarette Sales to Minors Prompts FDA to Crack Down – APhA submits compounding comments to FDA.

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Increasing E-Cigarette Sales to Minors Prompts FDA to Crack Down – APhA submits compounding comments to FDA. – (866) 348-2889.

E-cigarettes can be beneficial tool for smoking cessation, but the use of e-cigarettes in minors can be dangerous. Despite the health risks associated with high levels of nicotine found in the e-cigarette pods, JUUL, a discrete e-cigarette designed to look like a USB flash drive, has become increasingly popular among youth.

JUUL is a rechargeable battery powered device that works by heating a mixture of flavored liquid and nicotine. The liquid becomes aerosolized for inhalation, with nicotine salts making it possible to inhale large quantities of nicotine without irritation, according to a statement released from the CDC.1

From 2016 to 2017, JUUL sales increased by more than 7-fold, growing to hold the highest share of the US e-cigarette market by the end of 2017, according to a CDC analysis of JUUL retail sales data, published by JAMA.1

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New Indication for Rivaroxaban Approved By FDA – Drug for nerve pain boosts high for opioid abusers.

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New Indication for Rivaroxaban Approved By FDA – Drug for nerve pain boosts high for opioid abusers. (866) 348-2889

A new indication for Janssen’s rivaroxaban (Xarelto) has been approved by FDA officials.

First approved by the FDA in 2011, the oral anticoagulant is now indicated for reducing the risk of major cardiovascular (CV) events, such as death, myocardial infarction (MI), and stroke, in people with chronic coronary or peripheral artery disease (CAD/PAD). The agency’s approval makes Xarelto the first and only Factor Xa inhibitor with the FDA’s backing for patients living with these conditions, according to Janssen.

“Despite the use of guideline-recommended therapies, patients with chronic CAD and/or PAD remain at risk of having a devastating and irreversible CV event,” said Paul Burton, MD, PhD, FACC, and Vice President of Medical Affairs, Internal Medicine, Janssen Scientific Affairs, LLC, in a prepared statement. “The new Xarelto vascular 2.5mg dose, when used with aspirin, represents a true breakthrough for patients with chronic CAD and PAD.”

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New Pharmacogenomics Certificate Program Available to Pharmacists – APhA submits compounding comments to FDA.

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New Pharmacogenomics Certificate Program Available to Pharmacists – APhA submits compounding comments to FDA. – (866) 348-2889.

A new Pharmacogenomics Certificate is available through the American Society of Health-System Pharmacists (ASHP). Announced Thursday, the certificate program is designed to teach pharmacists how to integrate pharmacogenomics into practice for improving medication use.1

This certificate joins other progams offering professional development courses in pharmacogenomics.2-5

Pharmacogenomics is a rapidly evolving field that evaluates how an individual’s genes affect his or her response to medications, according to ASHP. The field allows medications to be prescribed to patients based on an individual’s genetic makeup, resulting in safer and more effective therapies.1

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Viral Video a Hit For Pharmacy Students and Dog – Drug for nerve pain boosts high for opioid abusers.

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Viral Video a Hit For Pharmacy Students and Dog – Drug for nerve pain boosts high for opioid abusers. (866) 348-2889

This hilarious video clip on Facebook recently caught my eye, but what caught my attention even more was the description: “Just in case you were wondering how pharmacy school is going…we may be a little brain dead already!”

After watching this video too many times, I reached out to its star.

Ashlynn Dacus, a P1 student at Harding University College of Pharmacy in Arkansas, was attempting to do a ‘What the Fluff’ challenge with her Saint Bernard, Maggie. In these videos, dog owners trick their dogs by hiding behind a large blanket, moving the blanket up and down a few times, and on the final move, the owner ducks into another room, and the confused dog looks for the owner.

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Arthritis Prevalent with Depressive Symptoms in Older Adults – APhA submits compounding comments to FDA.

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Arthritis Prevalent with Depressive Symptoms in Older Adults – APhA submits compounding comments to FDA. – (866) 348-2889.

A new study has found that arthritis is commonly reported in older adults with varying degrees of depression, highlighting the importance of screening and treating arthritis-related pain in these patients.

The study, published in the International Journal of Geriatric Psychiatry, set out to determine arthritis rates among older adults in the United States with depressive symptoms. The researchers used National Health and Nutrition Examination Survey data from 2011 to 2014 to identify participants aged 50 years and older with depressive symptoms and self-reported physician-diagnosed arthritis.

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